Surgical KIS

Surgical Knotless Innovation Solutions

Surgical-KIS

Surgical KIS is developing SLEEK, a unique and innovative solution to lower the risks attributed to valve replacement in open heart surgery .

Our approach with SLEEK is to simplify the procedure as much as possible and to cut a significant amount of time needed in completing the procedure with the current method used of hand tying the suitors .

Market and Business Opportunity

The open-heart valve surgery market in the USA is estimated at over 80,000 procedures per year, costing $80,000 and above per procedure and having a total market value of about $6 billion. Our product targets the specific market of connecting the valve to the heart. The cost of sutures is $100-$200, and the competing product is priced at $1,000-$2,000, so the specific market is estimated at more than $100 million.

The USA is the most significant market in terms of the price hospitals are willing to pay for products similar to ours. The number of procedures in Europe is relatively similar to the numbers in the USA, but the price obtainable for the products is lower, so the market is estimated at more than $100 million.

The Need

Specifically, the critical stage of attaching the artificial valve to the heart tissues presents many difficulties:

  • Prolonged surgery time: Suturing 14-18 threads, each requiring 6-8 knots, significantly extends the surgery time.
  • Increased risk: The longer the connection to the heart-lung machine, the greater the risk of clinical complications.
  • Precision and skill: High skill is required to perform the knots accurately, neither too tight nor too loose.
  • Limited access: The surgeon deals with complicated and challenging access to the valve.
  • Risk of damage: Overly aggressive tying can damage tissues, while overly loose tying can cause leaks and additional complications.

    • SLEEK

    The system, designed to be pre-woven into the suture, allows the surgeon to perform all regular surgical procedures up to the critical stage of tying the suture. When activated, the system tightens and locks through a simple and quick pull, easing the surgeon’s task at this crucial stage and ensuring precise attachment without metal parts remaining in the patient’s body.

    The product consists of two main parts. The first is the system suture, which forms the system’s core. It’s a standard suture for valve surgeries that have been manipulated to include a self-tightening and locking mechanism. The second part is the Pusher and Cutter, which creates counter-tension for pulling the suture and cuts the excess suture at the end of the process.

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    Advantages

    Our findings demonstrated that our SLEEK would help lower the risk.

  • 1 Safe: Outstanding safety profile, fewer procedure-related adverse outcomes
  • 2 Effective: Fast
  • 3 Easy and intuitive to use, for a variety of personnel with different levels of expertise
  • 4 Cost effective

    • Seeking

    • Strategic collaboration
    • Investment for IND

    www.KIS-Surgical.com

    SLEEK

    Investment Profile

    • Validated need by surgeons
    • Superior performance over current solutions
    • Highly experienced management team
    • strong IP

    Intellectual Property

    under construction .

    Management Team

    • Mr. Amit Ashkenazi (ENG) CEO Has an extensive experience in the medical device arena for more than 22 years. On his record are senior executive positions such as the CEO of Intratech Medical Ltd, and President & CEO of Keystone Heart, which was acquired by Venus Medtech (2500.HK). Experienced in leading significant teams with track records of building a full-blown company, and selling devices in the cardiac field. Among his responsibilities He built an innovation center developing various solutions for cardiovascular applications, managing R&D teams simultaneously in several medical device startups, leading multidisciplinary R&D teams from a concept to commercialization. Amit holds a BSc in mathematics and computer science.
    • Dr. Yuval Shezifi- CTO – Co Founder Dr. Shezifi is a Medical Device Specialist, with over 20 years of “Hands on” experience in implant devices in the fields of orthopedics – spine, tendons and ligaments mending, neurology – aneurysm treatment, sensory patches, cardiovascular – stenosis, embolic protection, medical textile – woven, versatile braiding, knotless suture:
      Innovative design, Developing, Hands on Manufacturing, Testing and clinical trials.
    • Prof. Isaac George – Medical Advisor Dr. Isaac George, MD joined NewYork Presbyterian/Columbia University Medical Center in the Department of Surgery in July of 2001 as a resident in general surgery following his graduation from Duke University School of Medicine. Prior to receiving his MD, Dr. George completed a B.S. in Mechanical Engineering at Massachusetts Institute of Technology in 1997. Dr. George also completed a fellowship program in cardiothoracic surgery in 2011 as well as a fellowship program in interventional cardiology in 2012. Dr. George is an Associate Professor of Surgery and Medicine, and the Surgical Director of Structural Heart of the NYP health system.
    • Prof. Gil Bolotin – Medical Advisor – Co Founder Specializes in the fields of heart valve repair and replacement, surgery of the aorta, surgical treatments for heart failure, robotic and minimally invasive cardiac surgery, and surgical treatments for atrial fibrillation.Prof. Bolotin graduated from the Faculty of Medicine at the Hebrew University in Jerusalem and completed his clinical training at the Department of Cardiothoracic Surgery at Carmel Medical Center in Haifa. He earned his Doctorate degree from the University of Maastricht, Netherlands. Prof. Bolotin has conducted extensive research regarding heart valve repair and replacement, surgery of the aorta, surgical treatments for heart failure, robotic and minimally invasive cardiac surgery, and surgical treatments for atrial fibrillation.

    Contact

    Email – Amit@surgicalKIS.com